We’ve heard of anti-oxidants. But what are they? Can they help my horse? Anti-oxidants are substances that help reduce oxidation within the body.
◆︎ Oxidation:
Oxidation is the chemical reaction that creates rust. It’s what causes tarnish on silverware.
It also occurs within the body at the cellular level. When excessive, or out of control, it damages DNA, proteins, and cells (think sun-damaged skin). Oxidation can also contribute to inflammation, previously discussed here.
There are many body systems that are particularly affected by oxidation. They include the skin, lungs, brain, and digestive system. It even affects the lining of blood vessels, which affects blood perfusion. As it can damage DNA, it can also negatively affect enzyme transcription. This can affect the holistic well-being of the horse.
◆︎ What are some examples of things that can increase oxidation?
☛ Radiation, including sunshine: Such as sun damage or x-rays
☛ Glucose intake: Think corn, oats, barley, millet, and other grains
☛ Vegetable oils high in omega 6: Some people like to add oil for a nice shiny coat and additional calories
☛ Iron and heavy metals: Iron and heavy metals are common contaminants in feed or the environment
☛ Pollution, including smoke from wildfires
☛ Pollen: Especially ragweed, mountain cedar, flowering plants (such as daisies and sunflowers)
☛ Chemicals: Cleaning solutions, some pesticides, cigarette smoke, air fresheners, paint
◆︎ Balancing act
With all the triggers for oxidation, it’s easy to think that oxidation is a bad thing. But some oxidation is necessary. For instance,
★ Iron bound in the red blood cells is responsible for carrying oxygen. That’s a good thing. But excess or unbound iron is not.
★ Glucose is necessary as fuel for our body. However, excess glucose intake can cause oxidative damage.
Obviously, it’s a balancing act between oxidation and anti-oxidants. It's important to have a good balance, especially under stress and compromised environments.
Our bodies are amazingly tolerant to the negative effects of oxidative damage, but additional support may be helpful.
◆︎ What are some of the supplements that may help reduce inflammation in the horse?
➡ Mov-Ease
➡ Spirulina powder or tablets
➡ MSM
➡ Hyaluronic acid: Especially high molecular weight
◆︎ More supplements that may help reduce oxidative stress
➡ CoQ10
These compounds work by either reducing the oxidative stress directly, or by increasing the activity of anti-oxidant enzymes. If you think of oxidation as rust within the body, these supplements may slow down the “rusting” process.
Interestingly, these are some of the same supplements that may reduce inflammation.
We do the best that we can for our horses. Understanding oxidative stress is a part of that.
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Disclaimer: Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
©Joan Kulifay 2025