In a previous issue, we discussed early arthritis and some of the nutritional supplements that may help our horse. (Available here) In this newsletter, we will discuss advanced arthritis.
Osteoartirits is frequently considered a condition of older horses. But it can develop at any age, depending on conformation, activity level and type of activity. It can also be secondary to a bacterial infection, injury, or disease.
We frequently miss the signs of early arthritis because they are so subtle. Horses are prey animals. The horse that limps first is the horse that’s eaten next. Because their survival depends on appearing to be in excellent health, they are very stoic and masters of deception. By the time we see the signs, they can no longer hide their lameness.
◆︎ Mechanisms of action:
Nutraceuticals frequently affect more than one mechanism of action.
☛ Mitochondrial support. The mitochondria frequently take a hit with oxidative processes. This can affect all of the cells involved in the systems of locomotion, such as the bone cells, the cells that create the articular fluid, muscles, and nerves.
☛ Nerve support. Some nutraceuticals are more adept at supporting the nerve cells, neuromuscular junctions, and nerve impulse transmissions.
☛ Downregulating the pain response. Some supplements also have the role of helping maintain a healthy pain response.
☛ Downregulation of inflammatory processes. Still other mechanisms are to bind to reactive oxygen species, to make them less active.
◆︎ Nutritional options for advanced arthritis:
While there are many choices available for advanced arthritis, many people experience better results by combining nutraceuticals.
Acetyl L-Carnitine: One of the main mechanisms of action is to support the mitochondria, including the mitochondria in nerve cells. Recommended serving size is 10 grams for a 1,000 lb. horse.
Coenzyme Q10: Supports the cells at the mitochondria level. It is also helpful in humans for muscle support, nerve support, and even migraines. Recommended serving size is 800 mg per day for a 1,000 lb. horse.
Devils Claw: Used extensively in osteoarthritis, due to reducing the inflammatory cytokines that accumulate within the joint. Recommended serving size is 2-9 grams per day for a 1,000 lb. horse of the Devil’s Claw 4:1.
Mov-Ease: Is a proprietary blend of bioflavonoids, which helps downregulate the pain response. Recommended serving size is 3 grams once or twice a day for a 1,000 lb. horse.
Quercetin: In humans, this has antioxidant, anti-inflammatory, and neuroprotective benefits. It is also helpful for those suffering from chronic inflammation. Recommended serving size is 2-5 grams once or twice a day for a 1,000 lb. horse.
Ultra-micronized PEA: PEA is created in every cell in the body. The small size of the ultra-micronized PEA has enhanced absorption. This is supportive for many different types of pain. However, studies have shown that extended treatment is usually necessary, of at least 60 days. Recommended serving size is 2.5-5 grams per day for a 1,000 lb. horse.
◆︎ Common combinations:
Some people find that the following combinations are helpful:
» Mov-ease + Ultra-micronized PEA
» Devils Claw + Turmeric
» Acetyl L-Carnitine + Ultra-micronized PEA
» Mov-ease + Acetyl L-Carnitine + Ultra-micronized PEA
With advanced arthritis, it’s important to remember that it did not occur overnight and you may not see the supporting effects of supplements for several weeks or even months. At some point, the arthritis may advance to a level that nutritional support isn’t enough.
We do the best we can for our horses. Giving support for arthritis is a part of that.
Disclaimer: Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
©Joan Kulifay 2024