Tendon issues occur in both humans and horses, frequently from overuse, aging, disease, or misuse.
When a tendon tear occurs, there are two main issues that affect healing. The first is that fibrotic scar tissue fills in the tear. This scar tissue is less organized and weaker than normal tendons.
The second issue is that the tendon cells may become “aged”, in that they stop dividing and stop creating new tendon cells.
Tendon treatment with corticosteroids
In the past, it was not unusual to treat tendon issues using corticosteroids, such as dexamethasone or triamcinolone. In horses, some veterinarians also thought steroid treatment was an accepted practice because it makes the tendon “look” good by reducing the swelling.
New studies show that when tendons are exposed to corticosteroids, some of the cells become “aged” – too old to divide. This results in poor healing, tissue disorganization, and increased scar tissue. This results in the structure being weaker than it otherwise might be.
Resveratrol to the rescue:
The study shows that oral resveratrol might be able to rescue aged tendon cells. Possible mechanisms include:
➡ Acting as an anti-inflammatory against the inflammatory cytokines to the damaged tendon.
➡ Inhibit fibrosis at the gene level.
➡ Inhibiting the signaling that the tendon cell is to “turn off” from dividing, especially the cells that have come in contact with corticosteroids. This allows the tendon cells to more readily divide.
➡ Potentially increasing the capillary bed and blood flow.
Take home message:
➡ Corticosteroids, such as dexamethasone or triamcinolone may be damaging the tendon that has been injured. Use caution and discuss thoroughly with your vet.
➡ Oral resveratrol may be helpful to support your horse’s healing from a damaged tendon.
➡ More research is needed, to better understand how to help our horses.
What to do?
Make informed decisions. The treatment for your horse should be based on informed decisions between you and your veterinarian.
We try to do the best we can for our horses. Knowing the drawbacks and options is one way that we can.
Disclaimer: Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.
©Joan Kulifay 2024